Traitement des pathologies articulaires inflammatoires.

Un concept novateur fondé sur l'immunomodulation par voie orale.

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Etudes cliniques

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Sécurité et efficacité du collagène de type II (UC-II®) seul, entrant dans la composition de Flextonic, dans le traitement de l’arthrite.

Traduction du Chapitre 21 d’un ouvrage intitulé “ARTHRITIS” écrit par Siba P. Raychaudhuri, Ramesh C. Gupta, Hiroyoshi Moriyama, Manashi Bagchi, Francis C. Lau, et Debasis Bagchi. Edité par CRC press

Use of Undenatured Type II Collagen in the Treatment of Rheumatoid Arthritis.

David E. Trentham, Andrew D. Halpner, Roselyn A. Trentham, Manashi Bagchi, Shil Kothari, Harry G. Preuss, Debasis Bagchi

Effects of Oral Administration of Type Il Collagen on Rheumatoid Arthritis.

David E. Trentham, Roselynn A. Dynesius-Trentham, E. John Orav, Daniel Combitchi, Carlos Lorenzo, Kathryn Lea Sewell, David A. Hafler, Howard L. Weiner

Treatment of Rhumatoid Arthritis Using Undenatured Type II Collagen.

David E. Trentham, Andrew D. Halpner, Roselyn A. Trentham, Manashi Bagchi, Shil Kothari, Harry G. Preuss, Debasis Bagchi

Oral type II collagen treatment in early rheumatoid arthritis.

Joachim Sieper, Sonja Kary, Helmut Sorensen, Rieke Alten, Ulrich Eggens, Werner Huge, Falk Hiepe, Andrea Kuhne, Joachim Listing, Norbert Ulbrich, Jurgen Braun, Angela Zink, and Nicholas Avrion Mitchison

Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial.

David C. Crowley, Francis C. Lau, Prachi Sharma, Malkanthi Evans, Najla Guthrie, Manashi Bagchi, Debasis Bagchi, Dipak K. Dey, Siba P. Raychaudhuri

Safety and toxicological evaluation of undenatured type II collagen.

Palma Ann Marone, Francis C. Lau, Ramesh C. Gupta, Manashi Bagchi, and Debasis Bagchi

Treatment of Rheumatoid Arthritis with Oral Type II Collagen.

Martha L. Barnett, Joel M. Kremer, E. William St. Clair, Daniel 0. Clegg, Daniel Furst, Michael Weisman, Malcolm J. F. Fletcher, Scott Chasan-Taber, Eduardo Finger, Alejandro Morales, Christine H. Le, and David E. Trentham

A Pilot Trial of Oral Type II Collagen in treatment of Juvenile Rheumatoid Arthritis.

Martha L. Barnett, Daniel Combitchi, and David E. Trentham

Effects of Orally administered undenatured Type 2 collagen against Artritic Inflamatory Desease - a mechanistic Exploration.

Bagchi D., Misner B., Bagchi M., Kothari S.C., Downs B.W., Preuss H.G.

A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis.

Wei Wei, Ling-Ling Zhang, Jian-Hua Xu, Feng Xiao, Chun-De Bao, Li-Qing Ni, Xing-Fu Li, Yu-Qing Wu, Ling-Yun Sun, Rong-Hua Zhang, Bao-Liang Sun, Sheng-Qian Xu, Shang Liu, Wei Zhang, Jie Shen, Hua-Xiang Liu and Ren-Cheng Wang

A Randomized, Double-Blind, Multicenter, Controlled Clinical Trial of Chicken Type II Collagen in Patients With Rheumatoid Arthritis.

Ling-Ling Zhang, Wei Wei, Feng Xiao, Jian-Hua Xu, Chun-De Bao, Li-Qing Ni, and Xing-Fu Li